Ontology highlight
ABSTRACT:
SUBMITTER: Rauen K
PROVIDER: S-EPMC7045352 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Rauen Katrin K Pop Viorela V Trabold Raimund R Badaut Jerome J Plesnila Nikolaus N
Journal of neurotrauma 20191204 4
Brain edema formation contributes to secondary brain damage and unfavorable outcome after traumatic brain injury (TBI). Aquaporins (AQP), highly selective water channels, are involved in the formation of post-trauma brain edema; however, their regulation is largely unknown. Because vasopressin receptors are involved in AQP-mediated water transport in the kidney and inhibition of V<sub>1a</sub> receptors reduces post-trauma brain edema formation, we hypothesize that cerebral AQPs may be regulated ...[more]