Ontology highlight
ABSTRACT:
SUBMITTER: Zernia S
PROVIDER: S-EPMC7045694 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Zernia Sarah S Zernia Sarah S van der Heide Nieck Jordy NJ Galenkamp Nicole Stéphanie NS Gouridis Giorgos G Maglia Giovanni G
ACS nano 20200207 2
Biological nanopores are emerging as powerful and low-cost sensors for real-time analysis of biological samples. Proteins can be incorporated inside the nanopore, and ligand binding to the protein adaptor yields changes in nanopore conductance. In order to understand the origin of these conductance changes and develop sensors for detecting metabolites, we tested the signal originating from 13 different protein adaptors. We found that the quality of the protein signal depended on both the size an ...[more]