Ontology highlight
ABSTRACT:
SUBMITTER: Ye YS
PROVIDER: S-EPMC7046846 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Ye Yan-Song YS Wu Man M Jiang Na-Na NN Lao Yuan-Zhi YZ Fu Wen-Wei WW Liu Xia X Yang Xing-Wei XW Zhang Juan J Xu Hong-Xi HX Xu Gang G
Natural products and bioprospecting 20200204 1
A series of dearomatized isoprenylated acylphloroglucinols derivatives, hyperhenols A-E (1-5), as well as seven known analogues (6-12), were characterized from Hypericum henryi. Their structures were determined by combination of NMR, ECD spectroscopy, and X-ray diffraction analysis. Compounds 1 and 6-8 were tested to exhibit potential antitumor properties, of which 6 and 7 inhibited cell growth through inducing apoptosis and cell cycle arrest. In addition, these compounds could induce autophagy ...[more]