Ontology highlight
ABSTRACT:
SUBMITTER: Xu S
PROVIDER: S-EPMC7047974 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Xu Shaohua S Liu Yiyun Y Pu Juncai J Gui Siwen S Zhong Xiaogang X Tian Lu L Song Xuemian X Qi Xunzhong X Wang Haiyang H Xie Peng P
Neuropsychiatric disease and treatment 20200224
<h4>Background</h4>Major depressive disorder (MDD) is a complex psychiatric illness involving multiple brain regions. Increasing evidence indicates that the striatum is involved in depression, but the molecular mechanisms remain unclear.<h4>Methods</h4>In this study, we performed a gas chromatography-mass spectrometer (GC/MS)-based metabolomic analysis in the striatum of depressed rats induced by chronic unpredictable mild stress (CUMS). We then compared striatal data with our previous data from ...[more]