Ontology highlight
ABSTRACT:
SUBMITTER: Gimeno-Valiente F
PROVIDER: S-EPMC7048834 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Gimeno-Valiente F F Riffo-Campos Á L ÁL Ayala G G Tarazona N N Gambardella V V Rodríguez F M FM Huerta M M Martínez-Ciarpaglini C C Montón-Bueno J J Roselló S S Roda D D Cervantes A A Franco L L López-Rodas G G Castillo J J
Scientific reports 20200228 1
The finding of novel molecular markers for prediction or prognosis of invasiveness in colorectal cancer (CRC) constitutes an appealing challenge. Here we show the up-regulation of EPDR1 in a prospective cohort of 101 CRC patients, in a cDNA array of 43 patients and in in silico analyses. EPDR1 encodes a protein related to ependymins, a family of glycoproteins involved in intercellular contacts. A thorough statistical model allowed us to conclude that the gene is significantly up-regulated in tum ...[more]