First-Line Systemic Treatments for Stage IV Non-Small Cell Lung Cancer in California: Patterns of Care and Outcomes in a Real-World Setting.

ABSTRACT:

Background

Multiple systemic treatments have been developed for stage IV non-small cell lung cancer (NSCLC), but their use and effect on outcomes at the population level are unknown. This study describes the utilization of first-line systemic treatments among stage IV NSCLC patients in California and compares survival among treatment groups.

Methods

Data on 17 254 patients diagnosed with stage IV NSCLC from 2012 to 2014 were obtained from the California Cancer Registry. Systemic treatments were classified into six groups. The Kaplan-Meier method and multivariable Cox proportional hazards models were used to compare survival between treatment groups.

Results

Fifty-one percent of patients were known to have received systemic treatment. For patients with nonsquamous hist

SUBMITTER: Maguire FB 

PROVIDER: S-EPMC7050031 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature