Ontology highlight
ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC7050086 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Chen Xi X Tian Falin F Li Min M Xu Haijiao H Cai Mingjun M Li Qian Q Zuo Xiaolei X Wang Hongda H Shi Xinghua X Fan Chunhai C Baigude Huricha H Shan Yuping Y
Global challenges (Hoboken, NJ) 20191120 3
DNA nanostructures have attracted considerable attention as drug delivery carriers. However, the transmembrane kinetics of DNA nanostructures remains less explored. Herein, the dynamic process of transporting single tetrahedral DNA nanostructures (TDNs) is monitored in real time using a force-tracing technique based on atomic force microscopy. The results show that transporting single TDNs into living HeLa cells need ≈53 pN force and ≈25 ms duration with the average speed of ≈0.6 µm s<sup>-1</su ...[more]