Ontology highlight
ABSTRACT:
SUBMITTER: Caprioli A
PROVIDER: S-EPMC7050435 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Caprioli Arianna A Villasenor Alethia A Wylie Lyndsay A LA Braitsch Caitlin C Marty-Santos Leilani L Barry David D Karner Courtney M CM Fu Stephen S Meadows Stryder M SM Carroll Thomas J TJ Cleaver Ondine O
Developmental biology 20150829 2
Wnt signaling is essential to many events during organogenesis, including the development of the mammalian lung. The Wnt family member Wnt4 has been shown to be required for the development of kidney, gonads, thymus, mammary and pituitary glands. Here, we show that Wnt4 is critical for proper morphogenesis and growth of the respiratory system. Using in situ hybridization in mouse embryos, we identify a previously uncharacterized site of Wnt4 expression in the anterior trunk mesoderm. This expres ...[more]