Interaction between postmenopausal hormone therapy and diabetes on cataract.

ABSTRACT:

Objective

We investigated whether postmenopausal hormone therapy (HT) use interacts with diabetes, a risk factor for several age-related eye diseases.

Methods

A cross-sectional analysis of women involved in the Canadian Longitudinal Study on Aging was performed. The random sample comprised of 15,320 community-dwelling women between ages 45 and 85 years old sampled from areas adjacent to 11 data collection centers across Canada. Information on menopausal status and HT were collected by self-report. Data on diabetes and eye disease were obtained by self-report of a physician diagnosis. Multivariable logistic regression was used.

Results

After adjusting for demographic, lifestyle, and health variables, a multiplicative interaction was identified such that HT use for 10 y

SUBMITTER: Costanian C 

PROVIDER: S-EPMC7050793 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature