Ontology highlight
ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC7052164 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Chen Xiangyu X Cao Guoshuai G Wu Jialin J Wang Xinxin X Pan Zhiwei Z Gao Jianbao J Tian Qin Q Xu Lifan L Li Zhirong Z Hao Yaxing Y Huang Qizhao Q Wang Pengcheng P Xiao Minglu M Xie Luoyingzi L Tang Shupei S Liu Zhenyu Z Hu Li L Tang Jianfang J He Ran R Wang Li L Zhou Xinyuan X Wu Yuzhang Y Chen Mengjie M Sun Beicheng B Zhu Bo B Huang Jun J Ye Lilin L
Cellular & molecular immunology 20190306 3
Epigenetic modifications to histones dictate the differentiation of naïve CD4<sup>+</sup> T cells into different subsets of effector T helper (T<sub>H</sub>) cells. The histone methyltransferase enhancer of zeste homolog 2 (EZH2) has been implicated in the mechanism regulating the differentiation of T<sub>H</sub>1, T<sub>H</sub>2 and regulatory T (T<sub>reg</sub>) cells. However, whether and how EZH2 regulates follicular helper T (T<sub>FH</sub>) cell differentiation remain unknown. Using a mous ...[more]