Ontology highlight
ABSTRACT:
SUBMITTER: Zhou J
PROVIDER: S-EPMC7052362 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhou Jiawei J Tang Ziwei Z Gao Siyang S Li Chunyu C Feng Yiting Y Zhou Xikun X
Frontiers in oncology 20200225
Macrophages, which have functions of engulfing and digesting foreign substances, can clear away harmful matter, including cellular debris and tumor cells. Based on the condition of the internal environment, circulating monocytes give rise to mature macrophages, and when they are recruited into the tumor microenvironment and in suitable conditions, they are converted into tumor-associated macrophages (TAMs). Generally, macrophages grow into two main groups called classically activated macrophages ...[more]