Ontology highlight
ABSTRACT:
SUBMITTER: Chen Y
PROVIDER: S-EPMC7053850 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Chen Yanyang Y Yin Hang H Tao Yong Y Zhong Shenxi S Yu Haoyang H Li Jianxiao J Bai Zhibiao Z Ou Yunsheng Y
International journal of molecular medicine 20200210 4
Photodynamic therapy (PDT) is a promising treatment for osteosarcoma, and pyropheophorbide‑α methyl ester (MPPa) is a second‑generation photosensitizer for tumor treatment. The present study aimed to determine the efficacy and possible mechanisms of MPPa‑PDT in the treatment of osteosarcoma MG‑63 cells. Flow cytometry and western blotting were used to detect cell cycle‑related indicators Cyclin D1, Cyclin E, Cyclin A and Cyclin B1. Cell migration and invasion abilities were detected using wound‑ ...[more]