Ontology highlight
ABSTRACT:
SUBMITTER: Hosek T
PROVIDER: S-EPMC7055233 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Hosek Tomas T Bougault Catherine M CM Lavergne Jean-Pierre JP Martinez Denis D Ayala Isabel I Fenel Daphna D Restelli Marine M Morlot Cecile C Habenstein Birgit B Grangeasse Christophe C Simorre Jean-Pierre JP
Scientific reports 20200304 1
MapZ localizes at midcell and acts as a molecular beacon for the positioning of the cell division machinery in the bacterium Streptococcus pneumoniae. MapZ contains a single transmembrane helix that separates the C-terminal extracellular domain from the N-terminal cytoplasmic domain. Only the structure and function of the extracellular domain is known. Here, we demonstrate that large parts of the cytoplasmic domain is intrinsically disordered and that there are two regions (from residues 45 to 6 ...[more]