Nickel Metalloregulators and Chaperones.
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ABSTRACT:
SUBMITTER: Higgins K
PROVIDER: S-EPMC7055735 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Publications
Nickel is essential for the survival of many pathogenic bacteria. <i>E. coli</i> and <i>H. pylori</i> require nickel for [NiFe]-hydrogenases. <i>H. pylori</i> also requires nickel for urease. At high concentrations nickel can be toxic to the cell, therefore, nickel concentrations are tightly regulated. Metalloregulators help to maintain nickel concentration in the cell by regulating the expression of the genes associated with nickel import and export. Nickel import into the cell, delivery of nic ...[more]
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