Ontology highlight
ABSTRACT:
SUBMITTER: Qiu Y
PROVIDER: S-EPMC7056622 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Data in brief 20200221
Bacterial transcription is a valid but underutilized target for antimicrobial agent discovery [1]. Nusbiarylins are the first-in-class bacterial ribosomal RNA synthesis inhibitors that possess potent activity against various types of multidrug-resistant bacteria with a novel mode of action by targeting the interaction of bacterial transcription factors NusB and NusE [2]. To facilitate the characterization of nusbiarylin derivatives produced by other researchers, high-performance liquid chromatog ...[more]