Ontology highlight
ABSTRACT:
SUBMITTER: Tabara K
PROVIDER: S-EPMC7056637 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Tabara Keisuke K Tamura Rie R Nakamura Aki A Mori Sachi S Kitano Takamichi T Fujikawa Koki K Fujikawa Mika M Okamoto Kazuaki K Kanayama Shoji S Uratsuji Hideya H Ikeda Fumiaki F Matsumoto Tatsumi T
The Journal of antibiotics 20200123 4
Ozenoxacin is a topical quinolone showing potent antimicrobial activities against Gram-negative and Gram-positive bacteria and is widely used for the treatment of inflammatory acne. However, the anti-inflammatory activities of ozenoxacin have not been examined so far. In the present study, we investigated the in vitro and in vivo anti-inflammatory effects of ozenoxacin. The production of interleukin (IL)-6 and IL-8 by human epidermal keratinocytes stimulated by heat-killed Cutibacterium acnes wa ...[more]