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ABSTRACT: Background
Hyperuricemia is a risk factor for cardiovascular diseases, but the impact of hyperuricemia and sex-related disparities is not fully clear in elderly patients with acute coronary syndrome (ACS).Objective
To investigate the association between hyperuricemia and 1-year all-cause mortality in elderly patients with ACS.Methods
This retrospective cohort study included 711 consecutive ACS patients aged ≥75 years, hospitalized in our center between January 2013 and December 2017. Serum uric acid (sUA), in-hospital events, and 1-year follow-up were analyzed. Multivariable logistic regression models were used to explore the risk factors for in-hospital events and 1-year all-cause mortality.Results
sUA levels were higher in males than in females (381.4 ± 110.1 vs. 349.3 ± 119.1 μmol/l, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, P < 0.001). Prevalence of hypertension (80.5% vs. 72.6%.Conclusions
Hyperuricemia is an independent risk factor for 1-year all-cause mortality in elderly female patients with ACS.
SUBMITTER: Tai S
PROVIDER: S-EPMC7057023 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Tai Shi S Li Xuping X Zhu Zhaowei Z Tang Liang L Yang Hui H Fu Liyao L Hu Xinqun X Fang Zhenfei Z Zhou Shenghua S
Cardiovascular therapeutics 20200222
<h4>Background</h4>Hyperuricemia is a risk factor for cardiovascular diseases, but the impact of hyperuricemia and sex-related disparities is not fully clear in elderly patients with acute coronary syndrome (ACS).<h4>Objective</h4>To investigate the association between hyperuricemia and 1-year all-cause mortality in elderly patients with ACS.<h4>Methods</h4>This retrospective cohort study included 711 consecutive ACS patients aged ≥75 years, hospitalized in our center between January 2013 and De ...[more]