Dataset Information

Distribution of congenital anomalies by race/ethnicity and geospatial location in Oklahoma, 1997-2009.

ABSTRACT:

Introduction

Congenital anomalies were the leading cause of infant mortality, responsible for 23 and 21% of deaths in Oklahoma and the USA, respectively, in 2016. We aimed to determine the prevalence by race/ethnicity and spatial distribution of congenital anomalies to identify geographic and racial/ethnic disparities, particularly among American Indian/Alaska Natives (AI/AN).

Methods

We evaluated the prevalence of anomalies by type and race/ethnicity among 648,074 live births in Oklahoma from 1997 to 2009. Prevalence proportion ratios (PPRs) and 95% confidence intervals (CIs) were calculated using Poisson regression. We used Moran's I and Getis-Ord Gi* to evaluate spatial clustering for neural tube defects, critical congenital heart defects (CCHDs), and oral clefts among births whose residence geocoded to the ZIP code or finer level.

Results

Overall prevalence of anomalies among live births was 3.9%. Non-Hispanic (NH) African American (PPR: 0.87, 95% CI: 0.83, 0.91), Asian/Pacific Islander (PPR: 0.70, 95% CI: 0.63, 0.78), and Hispanic (PPR: 0.87, 95% CI: 0.83, 0.91) children had a lower prevalence of anomalies compared to NH whites. The prevalence in NH AI/AN children was similar to NH whites (PPR: 1.01, 95% CI: 0.97, 1.05). However, differences in specific types of anomalies were observed by race/ethnicity. We observed no spatial autocorrelation for CCHD and oral clefts. Neural tube defects demonstrated spatial autocorrelation (p DiscussionThe prevalence of anomalies by race/ethnicity and geography differed by race/ethnicity and region, though this varied by anomaly. Additional research is needed to identify behavioral or environmental factors to target for prevention.

SUBMITTER: Janitz AE

PROVIDER: S-EPMC7057226 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Distribution of congenital anomalies by race/ethnicity and geospatial location in Oklahoma, 1997-2009.

Janitz Amanda E AE Dao Hanh Dung HD Campbell Janis E JE Stoner Julie A JA Peck Jennifer D JD

Birth defects research 20191210 3

<h4>Introduction</h4>Congenital anomalies were the leading cause of infant mortality, responsible for 23 and 21% of deaths in Oklahoma and the USA, respectively, in 2016. We aimed to determine the prevalence by race/ethnicity and spatial distribution of congenital anomalies to identify geographic and racial/ethnic disparities, particularly among American Indian/Alaska Natives (AI/AN).<h4>Methods</h4>We evaluated the prevalence of anomalies by type and race/ethnicity among 648,074 live births in ...[more]

PMID: 31820848

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Dataset Information

Distribution of congenital anomalies by race/ethnicity and geospatial location in Oklahoma, 1997-2009.

Introduction

Methods

Results

Publications

Distribution of congenital anomalies by race/ethnicity and geospatial location in Oklahoma, 1997-2009.

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