Ontology highlight
ABSTRACT:
SUBMITTER: Spurr LF
PROVIDER: S-EPMC7058180 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Spurr Liam F LF Alomran Nawaf N Bousounis Pavlos P Reece-Stremtan Dacian D Prashant N M NM Liu Hongyu H Słowiński Piotr P Li Muzi M Zhang Qianqian Q Sein Justin J Asher Gabriel G Crandall Keith A KA Tsaneva-Atanasova Krasimira K Horvath Anelia A
Bioinformatics (Oxford, England) 20200301 5
<h4>Motivation</h4>By testing for associations between DNA genotypes and gene expression levels, expression quantitative trait locus (eQTL) analyses have been instrumental in understanding how thousands of single nucleotide variants (SNVs) may affect gene expression. As compared to DNA genotypes, RNA genetic variation represents a phenotypic trait that reflects the actual allele content of the studied system. RNA genetic variation at expressed SNV loci can be estimated using the proportion of al ...[more]