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Epigenetics in age-related macular degeneration: new discoveries and future perspectives.

ABSTRACT: The study of epigenetics has explained some of the 'missing heritability' of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD. This 'AMD epigenome' may offer the chance to develop novel AMD treatments.

SUBMITTER: Gemenetzi M

PROVIDER: S-EPMC7058675 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Epigenetics in age-related macular degeneration: new discoveries and future perspectives.

Gemenetzi M M Lotery A J AJ

Cellular and molecular life sciences : CMLS 20200102 5

The study of epigenetics has explained some of the 'missing heritability' of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD. This 'AMD epigenome' may offer the chance to develop novel AMD treatments. ...[more]

PMID: 31897542

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