The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.
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ABSTRACT:
SUBMITTER: Yang H
PROVIDER: S-EPMC7066251 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.
Yang Hui H Wang Kunlun K Wang Tao T Li Mengxi M Li Bingxu B Li Shenglei S Yuan Ling L
Frontiers in oncology 20200305
Esophageal cancer (EC) is one of the most common cancers with poor survival in the world. Nowadays, a generous number of clinical trials are underway on the use of immunotherapy in EC patients, especially the programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors. However, only a few patients could benefit from single-agent therapy. Others need combination therapies to enhance the response rate and survival. In this review, we focus on PD-1/PD-L1 inhibitors and its combination opti ...[more]
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