Ontology highlight
ABSTRACT:
SUBMITTER: Xu L
PROVIDER: S-EPMC7066930 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Xu Li L Wang Hongjiang H Jiang Feng F Sun Hao H Zhang Dapeng D
Aging 20200221 4
Hearts often undergo abnormal remodelling and hypertrophic growth in response to pathological stress. Long non-coding RNAs (LncRNAs) can change cardiac function and participate in regulation of cardiac hypertrophy. The present study aims to identify the role of AK045171 in cardiac hypertrophy and the underlying mechanism in hypertrophic cascades. Mice with cardiac hypertrophy were established through transverse aortic constriction (TAC). Cardiac hypertrophy in cardiomyocytes was induced by angio ...[more]