Ontology highlight
ABSTRACT:
SUBMITTER: Yokoyama-Kokuryo W
PROVIDER: S-EPMC7068901 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Yokoyama-Kokuryo Waka W Yamazaki Hayato H Takeuchi Tsutomu T Amano Koichi K Kikuchi Jun J Kondo Tsuneo T Nakamura Seiji S Sakai Ryoko R Hirano Fumio F Nanki Toshihiro T Koike Ryuji R Harigai Masayoshi M
Arthritis research & therapy 20200312 1
<h4>Background</h4>Abatacept (ABA) is a biological disease-modifying antirheumatic drug (bDMARD) for rheumatoid arthritis (RA). The aim of this study was to identify molecules that are associated with therapeutic responses to ABA in patients with RA.<h4>Methods</h4>Peripheral blood was collected using a PAX gene Blood RNA kit from 45 bDMARD-naïve patients with RA at baseline and at 6 months after the initiation of ABA treatment. Gene expression levels of responders (n = 27) and non-responders (n ...[more]