Transcriptomics

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Gene expression profiling in Abatacept treated Rheumatoid Arthritis patients according to response


ABSTRACT: The objective of this study was to identify specific gene expression profiles able to predict the response of rheumatoid arthritis patients treated with methotrexate /abatacept (Aba). Thirty six RA patients were received Abatacept. The drug efficacy was evaluated with the DAS28 score after 6 months of treatment according to the EULAR response criteria. Among 36 Aba RA patients, 17 were responders and 19 were classified as no-responders. A blood sample was carried out in patients just before the first injection of treatment in PaxGene tubes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE68215 | GEO | 2017/05/17

SECONDARY ACCESSION(S): PRJNA282038

REPOSITORIES: GEO

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