Ontology highlight
ABSTRACT:
SUBMITTER: Lucchetti D
PROVIDER: S-EPMC7072373 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Lucchetti Donatella D Colella Filomena F Perelli Luigi L Ricciardi-Tenore Claudio C Calapà Federica F Fiori Micol E ME Carbone Federica F De Maria Ruggero R Sgambato Alessandro A
Cancers 20200121 2
Cancer cells secrete small extracellular vesicles (sEVs) that are involved in the remodeling of tumor microenvironment (TME) and can promote tumor progression. The role of sEVs and their molecular key players in colon cancer stem cells differentiation are poorly understood. This study aimed to analyze the role and content of sEVs released during the differentiation of colorectal cancer stem cells. Here we show that sEVs secretion during colon cancer stem cells differentiation is partially contro ...[more]