Ontology highlight
ABSTRACT:
SUBMITTER: Quaglia F
PROVIDER: S-EPMC7448905 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Quaglia Fabio F Krishn Shiv Ram SR Daaboul George G GG Sarker Srawasti S Pippa Raffaella R Domingo-Domenech Josep J Kumar Gaurav G Fortina Paolo P McCue Peter P Kelly William K WK Beltran Himisha H Liu Qin Q Languino Lucia R LR
Journal of extracellular vesicles 20200524 1
The ability of small extracellular vesicles (sEVs) to reprogram cancer cells is well established. However, the specific sEV components able to mediate aberrant effects in cancer cells have not been characterized. Integrins are major players in mediating sEV functions. We have previously reported that the αVβ3 integrin is detected in sEVs of prostate cancer (PrCa) cells and transferred into recipient cells. Here, we investigate whether sEVs from αVβ3-expressing cells affect tumour growth differen ...[more]