Ontology highlight
ABSTRACT:
SUBMITTER: Allegra A
PROVIDER: S-EPMC7072434 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Allegra Alessandro A Musolino Caterina C Tonacci Alessandro A Pioggia Giovanni G Casciaro Marco M Gangemi Sebastiano S
Cancers 20200224 2
B-cell chronic lymphocytic leukemia (B-CLL) is the main cause of mortality among hematologic diseases in Western nations. B-CLL is correlated with an intense alteration of the immune system. The altered functions of innate immune elements and adaptive immune factors are interconnected in B-CLL and are decisive for its onset, evolution, and therapeutic response. Modifications in the cytokine balance could support the growth of the leukemic clone via a modulation of cellular proliferation and apop ...[more]