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Advances in Chemistry and Bioactivity of Magnoflorine and Magnoflorine-Containing Extracts.

ABSTRACT: The review collects together some recent information on the identity and pharmacological properties of magnoflorine, a quaternary aporphine alkaloid, that is widely distributed within the representatives of several botanical families like Berberidaceae, Magnoliaceae, Papaveraceae, or Menispermaceae. Several findings published in the scientific publications mention its application in the treatment of a wide spectrum of diseases including inflammatory ones, allergies, hypertension, osteoporosis, bacterial, viral and fungal infections, and some civilization diseases like cancer, obesity, diabetes, dementia, or depression. The pharmacokinetics and perspectives on its introduction to therapeutic strategies will also be discussed.

SUBMITTER: Okon E

PROVIDER: S-EPMC7072879 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Advances in Chemistry and Bioactivity of Magnoflorine and Magnoflorine-Containing Extracts.

Okon Estera E Kukula-Koch Wirginia W Jarzab Agata A Halasa Marta M Stepulak Andrzej A Wawruszak Anna A

International journal of molecular sciences 20200216 4

The review collects together some recent information on the identity and pharmacological properties of magnoflorine, a quaternary aporphine alkaloid, that is widely distributed within the representatives of several botanical families like Berberidaceae, Magnoliaceae, Papaveraceae, or Menispermaceae. Several findings published in the scientific publications mention its application in the treatment of a wide spectrum of diseases including inflammatory ones, allergies, hypertension, osteoporosis, b ...[more]

PMID: 32079131

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