Lipids and Alzheimer's Disease.
Ontology highlight
ABSTRACT:
SUBMITTER: Kao YC
PROVIDER: S-EPMC7073164 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
Lipids and Alzheimer's Disease.
Kao Yu-Chia YC Ho Pei-Chuan PC Tu Yuan-Kun YK Jou I-Ming IM Tsai Kuen-Jer KJ
International journal of molecular sciences 20200222 4
Lipids, as the basic component of cell membranes, play an important role in human health as well as brain function. The brain is highly enriched in lipids, and disruption of lipid homeostasis is related to neurologic disorders as well as neurodegenerative diseases such as Alzheimer's disease (AD). Aging is associated with changes in lipid composition. Alterations of fatty acids at the level of lipid rafts and cerebral lipid peroxidation were found in the early stage of AD. Genetic and environmen ...[more]
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