Ontology highlight
ABSTRACT:
SUBMITTER: Di Paolo G
PROVIDER: S-EPMC3321383 | biostudies-other | 2011 May
REPOSITORIES: biostudies-other
Di Paolo Gilbert G Kim Tae-Wan TW
Nature reviews. Neuroscience 20110330 5
Lipid-mediated signalling regulates a plethora of physiological processes, including crucial aspects of brain function. In addition, dysregulation of lipid pathways has been implicated in a growing number of neurodegenerative disorders, such as Alzheimer's disease (AD). Although much attention has been given to the link between cholesterol and AD pathogenesis, growing evidence suggests that other lipids, such as phosphoinositides and phosphatidic acid, have an important role. Regulators of lipid ...[more]