Ontology highlight
ABSTRACT:
SUBMITTER: Pepe F
PROVIDER: S-EPMC7074107 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Journal of clinical medicine 20200221 2
In the past decade, novel targeted therapy approaches, such as BTK inhibitors and Bcl2 blockers, and innovative treatments that regulate the immune response against cancer cells, such as monoclonal antibodies, CAR-T cell therapy, and immunomodulatory molecules, have been established to provide support for the treatment of patients. However, drug resistance development and relapse are still major challenges in CLL treatment. Several studies revealed that non-coding RNAs have a main role in the de ...[more]