Ontology highlight
ABSTRACT:
SUBMITTER: Calmeiro J
PROVIDER: S-EPMC7076373 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Calmeiro João J Carrascal Mylène A MA Tavares Adriana Ramos AR Ferreira Daniel Alexandre DA Gomes Célia C Falcão Amílcar A Cruz Maria Teresa MT Neves Bruno Miguel BM
Pharmaceutics 20200215 2
Throughout the last decades, dendritic cell (DC)-based anti-tumor vaccines have proven to be a safe therapeutic approach, although with inconsistent clinical results. The functional limitations of ex vivo monocyte-derived dendritic cells (MoDCs) commonly used in these therapies are one of the pointed explanations for their lack of robustness. Therefore, a great effort has been made to identify DC subsets with superior features for the establishment of effective anti-tumor responses and to apply ...[more]