Ontology highlight
ABSTRACT:
SUBMITTER: Salvanou EA
PROVIDER: S-EPMC7076693 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Salvanou Evangelia-Alexandra EA Stellas Dimitris D Tsoukalas Charalampos C Mavroidi Barbara B Paravatou-Petsotas Maria M Kalogeropoulos Nikolaos N Xanthopoulos Stavros S Denat Franck F Laurent Gautier G Bazzi Rana R Roux Stephane S Bouziotis Penelope P
Pharmaceutics 20200221 2
Actinium-225 (<sup>225</sup>Ac) is receiving increased attention for its application in targeted radionuclide therapy, due to the short range of its emitted alpha particles in conjunction with their high linear energy transfer, which lead to the eradication of tumor cells while sparing neighboring healthy tissue. The objective of our study was the evaluation of a gold nanoparticle radiolabeled with <sup>225</sup>Ac as an injectable radiopharmaceutical form of brachytherapy for local radiation tr ...[more]