Ontology highlight
ABSTRACT:
SUBMITTER: VanHecke GC
PROVIDER: S-EPMC7078011 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Chembiochem : a European journal of chemical biology 20191029 6
Protein S-glutathionylation is one of the important cysteine oxidation events that regulate various redox-mediated biological processes. Despite several existing methods, there are few proteomic approaches to identify and quantify specific cysteine residues susceptible to S-glutathionylation. We previously developed a clickable glutathione approach that labels intracellular glutathione with azido-Ala by using a mutant form of glutathione synthetase. In this study, we developed a quantification s ...[more]