Unknown

Dataset Information

0

Recent Advance in Source, Property, Differentiation, and Applications of Infrapatellar Fat Pad Adipose-Derived Stem Cells.


ABSTRACT: Infrapatellar fat pad (IPFP) can be easily obtained during knee surgery, which avoids the damage to patients for obtaining IPFP. Infrapatellar fat pad adipose-derived stem cells (IPFP-ASCs) are also called infrapatellar fat pad mesenchymal stem cells (IPFP-MSCs) because the morphology of IPFP-ASCs is similar to that of bone marrow mesenchymal stem cells (BM-MSCs). IPFP-ASCs are attracting more and more attention due to their characteristics suitable to regenerative medicine such as strong proliferation and differentiation, anti-inflammation, antiaging, secreting cytokines, multipotential capacity, and 3D culture. IPFP-ASCs can repair articular cartilage and relieve the pain caused by osteoarthritis, so most of IPFP-related review articles focus on osteoarthritis. This article reviews the anatomy and function of IPFP, as well as the discovery, amplification, multipotential capacity, and application of IPFP-ASCs in order to explain why IPFP-ASC is a superior stem cell source in regenerative medicine.

SUBMITTER: Zhong YC 

PROVIDER: S-EPMC7081037 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

altmetric image

Publications

Recent Advance in Source, Property, Differentiation, and Applications of Infrapatellar Fat Pad Adipose-Derived Stem Cells.

Zhong Yu-Chen YC   Wang Shi-Chun SC   Han Yin-He YH   Wen Yu Y  

Stem cells international 20200307


Infrapatellar fat pad (IPFP) can be easily obtained during knee surgery, which avoids the damage to patients for obtaining IPFP. Infrapatellar fat pad adipose-derived stem cells (IPFP-ASCs) are also called infrapatellar fat pad mesenchymal stem cells (IPFP-MSCs) because the morphology of IPFP-ASCs is similar to that of bone marrow mesenchymal stem cells (BM-MSCs). IPFP-ASCs are attracting more and more attention due to their characteristics suitable to regenerative medicine such as strong prolif  ...[more]

Similar Datasets

| S-EPMC4085024 | biostudies-literature
| S-EPMC4129979 | biostudies-literature
| S-EPMC8739472 | biostudies-literature
| S-EPMC8615266 | biostudies-literature
| S-EPMC3582830 | biostudies-literature
| S-EPMC7792122 | biostudies-literature
| S-EPMC4829842 | biostudies-literature
| S-EPMC8841120 | biostudies-literature
| S-EPMC9869593 | biostudies-literature
| S-EPMC9434820 | biostudies-literature