Ontology highlight
ABSTRACT:
SUBMITTER: Steinbruch M
PROVIDER: S-EPMC7081038 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Steinbruch Marcio M Nunes Carlos C Gama Romualdo R Kaufman Renato R Gama Gustavo G Suchmacher Neto Mendel M Nigri Rafael R Cytrynbaum Natasha N Brauer Oliveira Lisa L Bertaina Isabelle I Verrière François F Geller Mauro M
International journal of vascular medicine 20200307
<h4>Background</h4>Phlebotonics have beneficial effects on some symptoms related to chronic venous disease (CVD) of the lower limbs. The most commonly used one is diosmin, available in a pure semisynthetic form or as a micronized purified flavonoid fraction. <i>Patients and Methods</i>. The primary objective of this single-blind, randomized, parallel-group, prospective study was to assess the clinical noninferiority of nonmicronized diosmin 600 mg once daily (D-group) compared to micronized dios ...[more]