Ontology highlight
ABSTRACT:
SUBMITTER: Stepniewska-Dziubinska MM
PROVIDER: S-EPMC7081267 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Stepniewska-Dziubinska Marta M MM Zielenkiewicz Piotr P Siedlecki Pawel P
Scientific reports 20200319 1
In recent years machine learning (ML) took bio- and cheminformatics fields by storm, providing new solutions for a vast repertoire of problems related to protein sequence, structure, and interactions analysis. ML techniques, deep neural networks especially, were proven more effective than classical models for tasks like predicting binding affinity for molecular complex. In this work we investigated the earlier stage of drug discovery process - finding druggable pockets on protein surface, that c ...[more]