Strategies for Neuroprotection in Multiple Sclerosis and the Role of Calcium.
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ABSTRACT:
SUBMITTER: Enders M
PROVIDER: S-EPMC7084497 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
Strategies for Neuroprotection in Multiple Sclerosis and the Role of Calcium.
Enders Michael M Heider Thorsten T Ludwig Andreas A Kuerten Stefanie S
International journal of molecular sciences 20200228 5
Calcium ions are vital for maintaining the physiological and biochemical processes inside cells. The central nervous system (CNS) is particularly dependent on calcium homeostasis and its dysregulation has been associated with several neurodegenerative disorders including Parkinson's disease (PD), Alzheimer's disease (AD) and Huntington's disease (HD), as well as with multiple sclerosis (MS). Hence, the modulation of calcium influx into the cells and the targeting of calcium-mediated signaling pa ...[more]
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