Ontology highlight
ABSTRACT:
SUBMITTER: Poudyal I
PROVIDER: S-EPMC7088463 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Structural dynamics (Melville, N.Y.) 20200320 2
X-ray free-electron lasers (XFELs) open the possibility of obtaining diffraction information from a single biological macromolecule. This is because XFELs can generate extremely intense x-ray pulses that are so short that diffraction data can be collected before the sample is destroyed. By collecting a sufficient number of single-particle diffraction patterns, the three-dimensional electron density of a molecule can be reconstructed <i>ab initio</i>. The quality of the reconstruction depends lar ...[more]