Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC7092830 | biostudies-literature | 2006 Sep
REPOSITORIES: biostudies-literature
Liu Yueyong Y Xu Yanhui Y Lou Zhiyong Z Zhu Jieqing J Hu Xuebo X Gao George F GF Qiu Bingsheng B Rao Zihe Z Tien Po P
Biochemical and biophysical research communications 20060804 3
The fusion proteins of enveloped viruses mediating the fusion between the viral and cellular membranes comprise two discontinuous heptad repeat (HR) domains located at the ectodomain of the enveloped glycoproteins. The crystal structure of the fusion protein core of Mumps virus (MuV) was determined at 2.2 A resolution. The complex is a six-helix bundle in which three HR1 peptides form a central highly hydrophobic coiled-coil and three HR2 peptides pack against the hydrophobic grooves on the surf ...[more]