Ontology highlight
ABSTRACT:
SUBMITTER: Li P
PROVIDER: S-EPMC7093024 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in microbiology 20200228
The influenza A virus (IAV) causes seasonal epidemics and occasional but devastating pandemics, which are of a major public health concern. Although several antiviral drugs are currently available, there is an urgent need to develop novel antiviral therapies with different mechanisms of action due to emergence of drug resistance. In this study, two related compounds, chebulagic acid (CHLA) and chebulinic acid (CHLI), were identified as novel inhibitors against IAV replication. A reporter virus-b ...[more]