Ontology highlight
ABSTRACT:
SUBMITTER: Hung HC
PROVIDER: S-EPMC7114187 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Antiviral research 20081117 2
There is a continuing threat that the highly pathogenic avian influenza virus will cause future influenza pandemics. In this study, we screened a library of compounds that are biologically active and structurally diverse for inhibitory activity against influenza neuraminidase (NA). We found that aurintricarboxylic acid (ATA) is a potent inhibitor of NA activity of both group-1 and group-2 influenza viruses with IC(50)s (effective concentration to inhibit NA activity by 50%) values at low micromo ...[more]