Ontology highlight
ABSTRACT:
SUBMITTER: Acosta-Ramirez E
PROVIDER: S-EPMC7094387 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Cellular immunology 20160712
Respiratory immunization is an attractive way to generate systemic and mucosal protective memory responses that are required for preventing mucosally transmitted infections. However, the molecular and cellular mechanisms for controlling memory T cell responses remain incompletely understood. In this study, we investigated the role of respiratory macrophage (MΦ) in regulating CD4 T cell responses to recombinant adenovirus-based (rAd) vaccines. We demonstrated that rAd intranasal (i.n.) vaccinatio ...[more]