Ontology highlight
ABSTRACT:
SUBMITTER: Requiao RD
PROVIDER: S-EPMC7096446 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Requião Rodrigo D RD Carneiro Rodolfo L RL Moreira Mariana Hoyer MH Ribeiro-Alves Marcelo M Rossetto Silvana S Palhano Fernando L FL Domitrovic Tatiana T
Scientific reports 20200325 1
Capsid proteins often present a positively charged arginine-rich sequence at their terminal regions, which has a fundamental role in genome packaging and particle stability for some icosahedral viruses. These sequences show little to no conservation and are structurally dynamic such that they cannot be easily detected by common sequence or structure comparisons. As a result, the occurrence and distribution of positively charged domains across the viral universe are unknown. Based on the net char ...[more]