Blood glucose and insulin concentrations after alpha-2-agonists administration in horses with and without insulin dysregulation.
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ABSTRACT:
SUBMITTER: Kritchevsky JE
PROVIDER: S-EPMC7096659 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
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Blood glucose and insulin concentrations after alpha-2-agonists administration in horses with and without insulin dysregulation.
Kritchevsky Janice E JE Muir Genevieve S GS Leschke Dakota H Z DHZ Hodgson Jack K JK Hess Emily K EK Bertin Francois-Rene FR
Journal of veterinary internal medicine 20200226 2
<h4>Background</h4>In metabolically stable horses, alpha-2-agonists suppress insulin secretion with transient hyperglycemia and rebound hyperinsulinemia. In horses with insulin dysregulation (ID), the effect of alpha-2-agonists has not been investigated; however, both the alpha-2-agonist-induced suppression of insulin secretion and rebound hyperinsulinemia could have clinical relevance.<h4>Hypothesis/objectives</h4>In horses with ID, alpha-2-agonists will alter insulin and glucose dynamics.<h4>A ...[more]
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