Ontology highlight
ABSTRACT:
SUBMITTER: Fabig G
PROVIDER: S-EPMC7101234 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Fabig Gunar G Kiewisz Robert R Lindow Norbert N Powers James A JA Cota Vanessa V Quintanilla Luis J LJ Brugués Jan J Prohaska Steffen S Chu Diana S DS Müller-Reichert Thomas T
eLife 20200310
Chromosome segregation during male meiosis is tailored to rapidly generate multitudes of sperm. Little is known about mechanisms that efficiently partition chromosomes to produce sperm. Using live imaging and tomographic reconstructions of spermatocyte meiotic spindles in <i>Caenorhabditis elegans</i>, we find the lagging X chromosome, a distinctive feature of anaphase I in <i>C. elegans</i> males, is due to lack of chromosome pairing. The unpaired chromosome remains tethered to centrosomes by l ...[more]