Ontology highlight
ABSTRACT:
SUBMITTER: Narjala A
PROVIDER: S-EPMC7102948 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Narjala Anushree A Nair Ashwin A Tirumalai Varsha V Hari Sundar G Vivek GV Shivaprasad Padubidri V PV
Nucleic acids research 20200401 6
Micro (mi)RNAs are 20-22nt long non-coding RNA molecules involved in post-transcriptional silencing of targets having high base-pair complementarity. Plant miRNAs are processed from long Pol II-transcripts with specific stem-loop structures by Dicer-like (DCL) 1 protein. Although there were reports indicating how a specific region is selected for miRNA biogenesis, molecular details were unclear. Here, we show that the presence of specific GC-rich sequence signature within miRNA/miRNA* region is ...[more]