Ontology highlight
ABSTRACT:
SUBMITTER: Khoshnevis S
PROVIDER: S-EPMC6885627 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20190919 48
Precise modification and processing of rRNAs are required for the production of ribosomes and accurate translation of proteins. Small nucleolar ribonucleoproteins (snoRNPs) guide the folding, modification, and processing of rRNAs and are thus critical for all eukaryotic cells. Bcd1, an essential zinc finger HIT protein functionally conserved in eukaryotes, has been implicated as an early regulator for biogenesis of box C/D snoRNPs and controls steady-state levels of box C/D snoRNAs through an un ...[more]