Dataset Information

Predictors of Improved Aerobic Capacity in Individuals With Chronic Stroke Participating in Cycling Interventions.

ABSTRACT:

Objective

To determine demographic and physiological factors that predict improvement in aerobic capacity among individuals with chronic stroke participating in cycling interventions.

Design

Secondary analysis of data from 2 randomized clinical trials.

Setting

Research laboratory.

Participants

Individuals with chronic stroke (N=44).

Interventions

Participants were randomized to one of the following interventions: forced aerobic exercise and upper extremity repetitive task practice (FE+UERTP, n=16), voluntary aerobic exercise and upper extremity repetitive task practice (VE+UERTP, n=15), or a nonaerobic control group (control, n=13). All interventions were time-matched and occurred 3 times per week for 8 weeks.

Main outcome measure

Aerobic capacity as measured by peak oxygen consumption per unit time (VO_2peak) during maximal cardiopulmonary exercise stress testing.

Results

Significant improvements in VO_2peak were observed from baseline to postintervention in the VE+UERTP group (P<.001). Considerable variability was observed among participants relating to postintervention change in VO_2peak. Among aerobic exercise participants, a multivariate regression analysis revealed that cycling cadence, baseline VO_2peak, and group allocation were significant predictors of change in VO_2peak.

Conclusions

High exercise rate (cycling cadence) appears to be an important variable in improving aerobic capacity and should be considered when prescribing aerobic exercise for individuals with chronic stroke. Those with low VO_2peak at baseline may benefit the most from aerobic interventions as it relates to cardiorespiratory fitness. Further investigation is warranted to understand the precise role of other exercise and demographic variables in the prescription of aerobic exercise for this population and their effects on secondary stroke prevention and mortality.

SUBMITTER: Linder SM

PROVIDER: S-EPMC7103502 | biostudies-literature |

REPOSITORIES: biostudies-literature

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