Role of rs454214 in Personality mediated Depression and Subjective Well-being.
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ABSTRACT:
SUBMITTER: Hou B
PROVIDER: S-EPMC7105480 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Publications
Role of rs454214 in Personality mediated Depression and Subjective Well-being.
Hou Binyin B Ji Lei L Chen Zhixuan Z An Lin L Zhang Naixin N Ren Decheng D Yuan Fan F Liu Liangjie L Bi Yan Y Guo Zhenming Z Ma Gaini G Xu Fei F Yang Fengping F Yu Shunying S Yi Zhenghui Z Xu Yifeng Y He Lin L Liu Chuanxin C Bai Bo B Wu Shaochang S Zhao Longyou L Zhao Longyou L Cai Changqun C Yu Tao T He Guang G Shi Yi Y Li Xingwang X
Scientific reports 20200330 1
Happiness and depression are interlinked and both heritable, while personality, as an important predictor of them, shares the genetic basis with them. We conjecture that genetic factors of depression can affect both depressive symptoms (DS) and subjective well-being (SWB), while personality traits play important roles in mediating this process. In this study, 878 Han Chinese college freshmen and 384 Han Chinese patients with the major depressive disorder (MDD) were included. SNPs were genotyped ...[more]
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